Effective Informal Learning: Considerations For The Workplace

This article consists of an academic librarian\u27s suggestions for an individual wanting to be a successful informal Learner in the workplace. Examples of modes of communication, scholarly activity, and education are explored, in addition to helpful mindsets and practical strategies for becoming an efficient and effective informal Learner. Discussion is given concerning an individual\u27s responsibilities and the environmental factors necessary for success in this type of learning. Prevailing climates and attitudes by administrators and employers are examined in addition to how these factors might influence learning of this typ

Extent Of Service: Minnesota Libraries Disability Services And Quality Of Websites: Assessing Public & Academic Libraries

This article addresses the availability of software/hardware and other sources for all persons with disabilities in Minnesota libraries, and also the navigability of websites of these libraries for those who are visually impaired. Many electronic resources are prohibitively difficult or impossible for the Blind to access. On a practical level, the article surveys and evaluates what is available and what works for people with disabilities at present. I surveyed all Academic Libraries and Public Library Systems in Minnesota as to their disability services, and evaluated the accessibility of library websites through the help of people with visual disabilities. The websites chosen were those of public Academic Libraries/Learning Resource Centers, and those of Public Libraries or Library Systems. To evaluate Minnesota library web sites, I was able to recruit 5 volunteers, and using their personal screen readers (JAWS 4. 0 or later), evaluated 20 Public Library and 40 public Academic Library web sites. Existing legislation concerning persons with disabilities is overviewed as well as issues and concerns that arose during the course of my writing and surveying. The work provides timely information and raises questions for further research

Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence.

BackgroundPatients with symptomatic intracranial atherosclerosis (ICAS) of ≥ 70% luminal stenosis are at high risk of stroke recurrence. We aimed to evaluate the relationships between hemodynamics of ICAS revealed by computational fluid dynamics (CFD) models and risk of stroke recurrence in this patient subset.MethodsPatients with a symptomatic ICAS lesion of 70-99% luminal stenosis were screened and enrolled in this study. CFD models were reconstructed based on baseline computed tomographic angiography (CTA) source images, to reveal hemodynamics of the qualifying symptomatic ICAS lesions. Change of pressures across a lesion was represented by the ratio of post- and pre-stenotic pressures. Change of shear strain rates (SSR) across a lesion was represented by the ratio of SSRs at the stenotic throat and proximal normal vessel segment, similar for the change of flow velocities. Patients were followed up for 1 year.ResultsOverall, 32 patients (median age 65; 59.4% males) were recruited. The median pressure, SSR and velocity ratios for the ICAS lesions were 0.40 (-2.46-0.79), 4.5 (2.2-20.6), and 7.4 (5.2-12.5), respectively. SSR ratio (hazard ratio [HR] 1.027; 95% confidence interval [CI], 1.004-1.051; P = 0.023) and velocity ratio (HR 1.029; 95% CI, 1.002-1.056; P = 0.035) were significantly related to recurrent territorial ischemic stroke within 1 year by univariate Cox regression, respectively with the c-statistics of 0.776 (95% CI, 0.594-0.903; P = 0.014) and 0.776 (95% CI, 0.594-0.903; P = 0.002) in receiver operating characteristic analysis.ConclusionsHemodynamics of ICAS on CFD models reconstructed from routinely obtained CTA images may predict subsequent stroke recurrence in patients with a symptomatic ICAS lesion of 70-99% luminal stenosis

Role of CARM1 in Regulating Qki-mediated Brain Cholesterol Biosynthesis

https://openworks.mdanderson.org/sumexp21/1089/thumbnail.jp

Receiver operating characteristic curves for shear strain rate ratio (left) and velocity ratio (right) to predict recurrent ischemic stroke in the territory of the qualifying artery.

<p>SIT indicates recurrent ischemic stroke in the territory of the qualifying artery; AUC, area under curve.</p

Kaplan-Meier curves for the cumulative probabilities of recurrent ischemic stroke in the territory (SIT) of the stenotic artery within 1 year after ictus, according to the shear strain rate (SSR) ratio (≥ or < median) as evaluated on the computational fluid dynamics models.

<p>Intracranial atherosclerotic lesions with a SSR ratio of ≥ median may relate to a higher risk of SIT, compared with lesions with a SSR ratio of < median (HR 5.483; 95% CI, 1.105–27.211; log-rank P = 0.079).</p

Kaplan-Meier curves for the cumulative probabilities of recurrent ischemic stroke in the territory (SIT) of the stenotic artery within 1 year after ictus, according to the velocity ratio (≥ or < median) as evaluated on the computational fluid dynamics models.

<p>Intracranial atherosclerotic lesions with a velocity ratio of ≥ median may relate to a higher risk of SIT, compared with lesions with a velocity ratio of < median (HR 5.483; 95% CI, 1.105–27.211; log-rank P = 0.079).</p

Evaluation of computational fluid dynamics model of an atherosclerotic lesion of left middle cerebral artery.

<p>A: Post- and pre-stenotic pressures were measured using spherical volumes-of-interest (VOI, double arrows) at the first anatomically normal diameters distal (VOI 1) and proximal (VOI 2) to the lesion, respectively. The pressure ratio was calculated by dividing the mean pressure at VOI 1 by the mean pressure at VOI 2. B: Shear strain rates (SSR) were respectively measured at the stenotic throat (cut-plane 1) and at the first anatomically normal diameter (cut-plane 2) proximal to the lesion, by using cut-planes perpendicular to the direction of blood flow (arrow). The SSR ratio was calculated by dividing the SSR averaged over cut-plane 1 by the SSR averaged over cut-plane 2. C: Velocities were similarly measured (arrow) as with the SSRs, and the velocity ratio was similarly calculated as with the SSR ratio.</p